Center |
Faculty of Medicine and Odontology |
Departament |
Biochemistry and Molecular Biology |
Lecturers in charge |
Sin datos cargados |
Met. Docent |
Seminarys,theorics and practics classes. |
Met. Avaluació |
Final exam. |
Bibliografia |
Norman Lavin. Manual de Endocrinología y Metabolismo Tomo I y II. Salvat Scriver, Beaudet, Valle, Sky. The Metabolic and Molecular Basis of Inherited Disease. Mc Graw-Hill Cohen, Lewis, Alberti, Denman. The Metabolic and Molecular Basis of Acquired Disease. Baillière-Tindall Norbert W. Tietz. Clinical Guide to Laboratory Test. Saunders Company José Manuel Gonzalez de Buitrago. Patología Molecular. MacGraw-Hill Paola Timiras. Bases Fisologicas del envejecimiento y geriatria. Masson |
Continguts |
Theory Program PART I. BIOCHEMICAL AND MOLECULAR BASES OF PATHOLOGY: 1. Molecular bases of illness 2. Free radicals and oxidative stress. Molecular mechanisms and Physiopathologicial Implications 3. Cell death. Degeneration, aging 4. Alterations in cell growth (neoplasia, discrasia and aplasia) 5. Inflammation 6. Molecular bases of clinical toxicology 7. Molecular bases of genetic illnesses 8. Alterations in recognition mechanisms and in the effectiveness of the immune system: hypersensitivity, auto-immunity and immuno-deficiency. PART II. ALTERATIONS IN THE CELLULAR METABOLISM 9. Metabolism of carbohydrates 10. Metabolism of amino acids 11. Metabolism of lipids and lipo-proteins 12. Metabolism of purines and pirimidines 13. Mitochondrial disease 14. Nutritional pathology 15. Metabolism of iron PART III. ALTERATIONS IN ORGANS AND TISSUES: THE NEXUS BETWEEN CLINICAL MANIFESTATIONS AND ANALYTIC DATA 16. Plasmatic proteins 17. Serum enzymes and their diagnostic value 18. Abnormal metabolites in urine 19. The hepatic and biliar function 20. Alterations in the |
Objetius |
Objectives: 1. To introduce the biochemical and molecular bases of the most relevant situations of metabolic alteration. 2. To introduce the biochemical and molecular aspects underlying the most relevant diagnostic procedures of the clinical analysis laboratory. |
URL de Fitxa |